RAD-140 & LGD-4033 REPLACEMENT
20 – E is the latest technology 100% Legal ‘herbal’ alternative that rapidly builds lean muscle (LGD-4033 replacement).
More Anabolic per MG than well known steroids such as Dianabol and Testosterone Propionate
Builds LEAN MUSCLE Fast!
Ideal for Men and Women!
20-E is an Anabolic Phytosteroid (APS), classified as an ecdysteroid. It is an anabolic compound, a natural effective muscle builder, an endurance and performance enhancer. It has 5% more anabolic activity then the traditional AAS Testosterone Propionate*.
Originally 20-hydroxyecdysone was studied and found to combat muscle atrophy and also stopped catabolic expression in cartilage at just 55mg/day HED. In the 1980s it was found to have profound effects surpassing the anabolic activity of many synthetic AAS.
What 20-E Does:
It exhibits a strong hypertrophic effect on muscle fibres 
Increases protein synthesis 
Is more hypertrophic then Methandienone (Dianabol), Estradienedione (Trenbolox), and the S-1
The active ingredient is banned by the World Doping Agency in
the Olympics  No androgenic activity, so no hormonal side effects  Safe for women
No PCT needed
Signals PI3K/Akt pathway, responsible for muscle cell growth and division
This is the same pathway IGF-1 uses for its muscle building effect
20-E has 5% more anabolic activity then the AAS Testosterone Propionate*
125mg/mL | 3.6mL/day | 428.4mg/day
1.8mL twice daily | one month supply
20-E contains 20-hydroxyecdysone ((2b,3b,5b,22r)-2,3,14,20,22,25-hexahydroxycholest-7-en-6-one), in a proprietary SMEDDS blend. The active compound is isolated from Brazilian Ginseng.
20-hydroxyecdysone has medium lipophilicity and requires SMEDDS to be efficient. Our proprietary SMEDDS blend is infused with caprylic acid a natural SARM.
To activate SMEDDS mix the recommended dose by stirring vigorously, shaking, or blending in water, milk, or juice.
Anabolic Activity of 20-E vs Testosterone Propionate
* Results according to Molinspiration molecular structure nuclear receptor bioactivity.
Hirunsai, M., Yimlamai, T. & Suksamrarn, A. 2016. Effect of 20-Hydroxyecdysone on Proteolytic Regulation in Skeletal Muscle Atrophy. International Journal of Experimental and Clinical Pathophysiology and Drug Research, 30(6), pp. 869-877. DOI: 10.21873/invivo.11007
Sheu, S. Y., Ho, S. R., Sun, J. S., Chen, C. Y. & Ke, C. J. 2015. Arthropod steroid hormone (20-Hydroxyecdysone) suppresses IL-1β- induced catabolic gene expression in cartilage. BMC Complementary and Alternative Medicine, 15(1). DOI: 10.1186/s12906-015-0520-z
Parr, M. K., Botre, F., Nab, A., Henjevoss, J., Diel, P. & Wolber, G. 2015. Ecdysteroids: A novel class of anabolic agents? Biology Of Sport, 32(2), pp. 169-173. DOI: 10.5604/20831862.1144420
Gorelick-Feldman, J., MacLean, D., Ilic, N., Poulev, A., Lila, M. A., Cheng, D., & Raskin, I. 2008. Phytoecdysteroids increase protein synthesis in skeletal muscle cells. Journal Of Agriculture And Food Chemistry, 56(10), pp. 3532-3537. DOI: 10.1021/jf073059z
Gorelick-Feldman, J., Cohick, W., & Raskin, I. 2010. Ecdysteroids elicit a rapid Ca 2+ flux leading to Akt activation and increased protein synthesis in skeletal muscle cells. Steroids, 75(10), pp. 632-637. DOI: 10.1016/j.steroids.2010.03.008
Syrov, V. N. & Kurmukov, A. G. 1976. Anabolic activity of phytoecdysone-ecdysterone isolated from Rhaponticum carthamoides (Willd.) Iljin. Farmakol Toksikol, 39(6), pp. 690-603. PMID 1030669
Parr, M. 2016. Ecdysteroids As Non-Conventional Anabolic Agents: Pharmacodynamics, Pharmacokinetics, And Detection OfEcdysterone. World Anti-Doping Agency. Freie Universität Berlin, Germany. Online Publication